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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2011 | 22 | A | MWL | SEA | 3 | 3 | .500 | 0 | 10 | 10 | 0 | 0 | 0 | 56.0 | 45 | 21 | 17 | 1 | 30 | 0 | 80 | 1 | 0 | 2.73 | 1.34 | | 2011 | 22 | AA | SOU | SEA | 3 | 0 | 1.000 | 0 | 7 | 7 | 0 | 0 | 0 | 39.0 | 28 | 10 | 8 | 2 | 13 | 0 | 51 | 1 | 0 | 1.85 | 1.05 | | 2012 | 23 | AA | SOU | SEA | 9 | 4 | .692 | 0 | 21 | 21 | 0 | 0 | 0 | 106.0 | 96 | 43 | 36 | 5 | 54 | 0 | 110 | 1 | 0 | 3.06 | 1.42 | | 2013 | 24 | AAA | PCL | SEA | 8 | 11 | .421 | 0 | 28 | 26 | 0 | 2 | 1 | 145.1 | 158 | 84 | 72 | 10 | 58 | 0 | 131 | 3 | 0 | 4.46 | 1.49 | | 2013 | 24 | MLB | AL | SEA | 3 | 0 | 1.000 | 0 | 4 | 4 | 0 | 0 | 0 | 24.0 | 15 | 5 | 4 | 2 | 7 | 2 | 21 | 0 | 1 | 1.50 | 0.92 | | 2014 | 25 | A- | NWL | SEA | 0 | 1 | .000 | 0 | 1 | 1 | 0 | 0 | 0 | 2.2 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 0 | 0 | 6.75 | 1.13 | | 2014 | 25 | AAA | PCL | SEA | 0 | 1 | .000 | 0 | 3 | 3 | 0 | 0 | 0 | 10.0 | 13 | 7 | 5 | 2 | 6 | 0 | 14 | 0 | 0 | 4.50 | 1.90 | | 2014 | 25 | MLB | AL | SEA | 6 | 4 | .600 | 0 | 13 | 13 | 0 | 0 | 0 | 74.0 | 60 | 29 | 25 | 3 | 29 | 2 | 59 | 1 | 9 | 3.04 | 1.20 | | 2015 | 26 | AAA | PCL | SEA | 0 | 1 | .000 | 0 | 3 | 3 | 0 | 0 | 0 | 6.2 | 12 | 6 | 6 | 0 | 3 | 0 | 4 | 0 | 0 | 8.10 | 2.25 | | 2015 | 26 | MLB | AL | SEA | 3 | 4 | .429 | 0 | 13 | 13 | 0 | 0 | 0 | 67.0 | 67 | 34 | 29 | 8 | 29 | 1 | 56 | 0 | 4 | 3.90 | 1.43 | | 2016 | 27 | AAA | PCL | SEA | 4 | 3 | .571 | 0 | 11 | 11 | 0 | 0 | 0 | 50.2 | 43 | 24 | 21 | 6 | 15 | 0 | 53 | 0 | 0 | 3.73 | 1.14 | | 2016 | 27 | MLB | AL | SEA | 6 | 7 | .462 | 0 | 20 | 20 | 0 | 0 | 0 | 121.0 | 134 | 62 | 51 | 9 | 24 | 3 | 117 | 1 | 17 | 3.79 | 1.31 | | 2017 | 28 | AA | TEX | | 0 | 0 | --- | 0 | 1 | 1 | 0 | 0 | 0 | 4.0 | 5 | 2 | 2 | 1 | 0 | 0 | 5 | 0 | 0 | 4.50 | 1.25 | | 2017 | 28 | MLB | AL | SEA | 12 | 5 | .706 | 0 | 24 | 24 | 0 | 0 | 0 | 136.0 | 113 | 47 | 45 | 9 | 37 | 1 | 156 | 3 | 7 | 2.98 | 1.10 | | 2018 | 29 | MLB | AL | SEA | 11 | 6 | .647 | 0 | 28 | 28 | 0 | 2 | 1 | 160.1 | 134 | 67 | 67 | 23 | 42 | 0 | 208 | 1 | 11 | 3.76 | 1.10 | | 2019 | 30 | MLB | AL | NYA | 15 | 6 | .714 | 0 | 29 | 29 | 0 | 0 | 0 | 150.2 | 138 | 71 | 64 | 23 | 55 | 0 | 186 | 2 | 9 | 3.82 | 1.28 | | 2020 | 31 | MLB | AL | NYA | 1 | 1 | .500 | 0 | 5 | 5 | 0 | 0 | 0 | 20.1 | 23 | 17 | 15 | 4 | 7 | 0 | 26 | 1 | 1 | 6.64 | 1.48 | | 2021 | 32 | MLB | AL | SEA | 0 | 0 | --- | 0 | 1 | 1 | 0 | 0 | 0 | 1.1 | 0 | 1 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 6.75 | 0.75 | | 2023 | 34 | MLB | AL | BOS | 7 | 5 | .583 | 0 | 19 | 19 | 0 | 0 | 0 | 96.0 | 93 | 51 | 48 | 18 | 33 | 0 | 101 | 2 | 6 | 4.50 | 1.31 | | 2024 | 35 | MLB | NL | LAN | 8 | 2 | .800 | 0 | 18 | 18 | 0 | 0 | 0 | 89.1 | 82 | 45 | 44 | 11 | 48 | 0 | 64 | 1 | 7 | 4.43 | 1.46 | | 2024 | 35 | MLB | AL | BOS | 1 | 1 | .500 | 0 | 3 | 3 | 0 | 0 | 0 | 11.0 | 13 | 8 | 5 | 1 | 2 | 0 | 9 | 0 | 2 | 4.09 | 1.36 | | 2024 | 35 | MLB | | TOT | 9 | 3 | .750 | 0 | 21 | 21 | 0 | 0 | 0 | 100.1 | 95 | 53 | 49 | 12 | 50 | 0 | 73 | 1 | 9 | 4.40 | 1.45 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 27 | 24 | .529 | 0 | 85 | 83 | 0 | 2 | 1 | 420.1 | 402 | 199 | 169 | 28 | 180 | 0 | 450 | 6 | 0 | 3.62 | 1.38 | | Career | SEA | 41 | 26 | .612 | 0 | 103 | 103 | 0 | 2 | 1 | 583.2 | 523 | 245 | 222 | 54 | 169 | 9 | 619 | 6 | 49 | 3.42 | 1.19 | | Career | NYA | 16 | 7 | .696 | 0 | 34 | 34 | 0 | 0 | 0 | 171.0 | 161 | 88 | 79 | 27 | 62 | 0 | 212 | 3 | 10 | 4.16 | 1.30 | | Career | BOS | 8 | 6 | .571 | 0 | 22 | 22 | 0 | 0 | 0 | 107.0 | 106 | 59 | 53 | 19 | 35 | 0 | 110 | 2 | 8 | 4.46 | 1.32 | | Career | LAN | 8 | 2 | .800 | 0 | 18 | 18 | 0 | 0 | 0 | 89.1 | 82 | 45 | 44 | 11 | 48 | 0 | 64 | 1 | 7 | 4.43 | 1.46 | | Career | Majors | 73 | 41 | .640 | 0 | 177 | 177 | 0 | 2 | 1 | 951.0 | 872 | 437 | 398 | 111 | 314 | 9 | 1005 | 12 | 74 | 3.77 | 1.25 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2013 | 24 | MLB | AL | SEA | | | | | | | | | | 3.2 | 5 | 1 | 1 | 0 | 1 | 0 | 5 | 0 | 0 | 2.45 | 1.64 | | 2013 | 24 | MLB | AL | SEA | | | | | | | | | | 20.1 | 10 | 4 | 3 | 2 | 6 | 2 | 16 | 0 | 1 | 1.33 | 0.79 | | 2014 | 25 | MLB | AL | SEA | | | | | | | | | | 12.1 | 9 | 5 | 5 | 0 | 6 | 0 | 14 | 0 | 1 | 3.65 | 1.22 | | 2014 | 25 | MLB | AL | SEA | | | | | | | | | | 61.2 | 51 | 24 | 20 | 3 | 23 | 2 | 45 | 1 | 8 | 2.92 | 1.20 | | 2015 | 26 | MLB | AL | SEA | | | | | | | | | | 11.1 | 23 | 14 | 12 | 2 | 10 | 0 | 14 | 0 | 1 | 9.53 | 2.91 | | 2015 | 26 | MLB | AL | SEA | | | | | | | | | | 55.2 | 44 | 20 | 17 | 6 | 19 | 1 | 42 | 0 | 3 | 2.75 | 1.13 | | 2016 | 27 | MLB | AL | SEA | | | | | | | | | | 19.0 | 21 | 7 | 7 | 1 | 7 | 0 | 11 | 0 | 3 | 3.32 | 1.47 | | 2016 | 27 | MLB | AL | SEA | | | | | | | | | | 102.0 | 113 | 55 | 44 | 8 | 17 | 3 | 106 | 1 | 14 | 3.88 | 1.27 | | 2017 | 28 | MLB | AL | SEA | | | | | | | | | | 23.0 | 17 | 7 | 7 | 0 | 4 | 0 | 22 | 1 | 1 | 2.74 | 0.91 | | 2017 | 28 | MLB | AL | SEA | | | | | | | | | | 113.0 | 96 | 40 | 38 | 9 | 33 | 1 | 134 | 2 | 6 | 3.03 | 1.14 | | 2018 | 29 | MLB | AL | SEA | | | | | | | | | | 23.2 | 34 | 19 | 19 | 3 | 7 | 0 | 38 | 1 | 1 | 7.23 | 1.73 | | 2018 | 29 | MLB | AL | SEA | | | | | | | | | | 136.2 | 100 | 48 | 48 | 20 | 35 | 0 | 170 | 0 | 10 | 3.16 | 0.99 | | 2019 | 30 | MLB | AL | NYA | | | | | | | | | | 36.2 | 38 | 15 | 12 | 2 | 9 | 0 | 46 | 1 | 2 | 2.95 | 1.28 | | 2019 | 30 | MLB | AL | NYA | | | | | | | | | | 114.0 | 100 | 56 | 52 | 21 | 46 | 0 | 140 | 1 | 7 | 4.11 | 1.28 | | 2020 | 31 | MLB | AL | NYA | | | | | | | | | | 5.0 | 6 | 4 | 3 | 1 | 0 | 0 | 5 | 1 | 0 | 5.40 | 1.20 | | 2020 | 31 | MLB | AL | NYA | | | | | | | | | | 15.1 | 17 | 13 | 12 | 3 | 7 | 0 | 21 | 0 | 1 | 7.04 | 1.57 | | 2021 | 32 | MLB | AL | SEA | | | | | | | | | | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | | 2021 | 32 | MLB | AL | SEA | | | | | | | | | | 1.0 | 0 | 1 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 9.00 | 1.00 | | 2023 | 34 | MLB | AL | BOS | | | | | | | | | | 20.1 | 24 | 10 | 8 | 3 | 10 | 0 | 16 | 0 | 0 | 3.54 | 1.67 | | 2023 | 34 | MLB | AL | BOS | | | | | | | | | | 75.2 | 69 | 41 | 40 | 15 | 23 | 0 | 85 | 2 | 6 | 4.76 | 1.22 | | 2024 | 35 | MLB | | TOT | | | | | | | | | | 19.0 | 18 | 3 | 3 | 1 | 4 | 0 | 13 | 0 | 4 | 1.42 | 1.16 | | 2024 | 35 | MLB | | TOT | | | | | | | | | | 81.1 | 77 | 50 | 46 | 11 | 46 | 0 | 60 | 1 | 5 | 5.09 | 1.51 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 174.1 | 195 | 85 | 77 | 13 | 58 | 0 | 184 | 4 | 13 | 3.98 | 1.45 | | Career | vs RH | | | | | | | | | | 776.2 | 677 | 352 | 321 | 98 | 256 | 9 | 821 | 8 | 61 | 3.72 | 1.20 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2013 | 24 | MLB | AL | SEA | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .500 | .000 | .500 | | 2014 | 25 | MLB | AL | SEA | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2015 | 26 | MLB | AL | SEA | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2016 | 27 | MLB | AL | SEA | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .250 | .000 | .250 | | 2019 | 30 | MLB | AL | NYA | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5 | 0 | 0 | 3 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | SEA | 5 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .222 | .000 | .222 | | Career | NYA | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5 | 0 | 0 | 3 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | Career | Majors | 8 | 12 | 1 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 12 | 0 | 0 | 4 | 0 | 0 | 0 | .000 | .143 | .000 | .143 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2013 | 24 | MLB | AL | SEA | | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | --- | --- | --- | --- | | 2013 | 24 | MLB | AL | SEA | | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .500 | .000 | .500 | | 2014 | 25 | MLB | AL | SEA | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2014 | 25 | MLB | AL | SEA | | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | --- | --- | --- | --- | | 2015 | 26 | MLB | AL | SEA | | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | --- | --- | --- | --- | | 2015 | 26 | MLB | AL | SEA | | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2016 | 27 | MLB | AL | SEA | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .500 | .000 | .500 | | 2016 | 27 | MLB | AL | SEA | | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2019 | 30 | MLB | AL | NYA | | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2019 | 30 | MLB | AL | NYA | | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | --- | --- | --- | --- | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | vs LH | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .125 | .000 | .125 | | Career | vs RH | | 5 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .167 | .000 | .167 |
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