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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2010 | 21 | A- | NYP | TB | 1 | 1 | .500 | 0 | 7 | 1 | 0 | 0 | 0 | 21.1 | 16 | 7 | 5 | 0 | 5 | 0 | 19 | 1 | 0 | 2.11 | 0.98 | | 2010 | 21 | A | MWL | TB | 0 | 1 | .000 | 0 | 5 | 2 | 0 | 0 | 0 | 16.1 | 15 | 15 | 13 | 1 | 8 | 0 | 10 | 2 | 0 | 7.16 | 1.41 | | 2011 | 22 | A+ | FSL | TB | 8 | 7 | .533 | 0 | 25 | 23 | 1 | 0 | 0 | 129.0 | 117 | 52 | 47 | 6 | 51 | 1 | 70 | 7 | 0 | 3.28 | 1.30 | | 2012 | 23 | AA | SOU | TB | 8 | 3 | .727 | 0 | 32 | 9 | 2 | 0 | 0 | 88.0 | 84 | 41 | 35 | 4 | 28 | 0 | 61 | 4 | 0 | 3.58 | 1.27 | | 2013 | 24 | AA | SOU | TB | 5 | 6 | .455 | 0 | 13 | 12 | 0 | 0 | 0 | 73.2 | 54 | 34 | 34 | 3 | 31 | 1 | 41 | 3 | 0 | 4.15 | 1.15 | | 2013 | 24 | AAA | INT | TB | 8 | 4 | .667 | 0 | 15 | 14 | 0 | 0 | 0 | 84.2 | 74 | 37 | 30 | 4 | 34 | 0 | 70 | 3 | 0 | 3.19 | 1.28 | | 2014 | 25 | AAA | INT | TB | 9 | 4 | .692 | 0 | 28 | 15 | 3 | 0 | 0 | 114.0 | 107 | 39 | 35 | 10 | 37 | 0 | 108 | 6 | 0 | 2.76 | 1.26 | | 2019 | 30 | MLB | NL | ARI | 13 | 14 | .481 | 0 | 32 | 32 | 0 | 0 | 0 | 183.1 | 184 | 95 | 90 | 29 | 57 | 4 | 158 | 2 | 14 | 4.42 | 1.31 | | 2020 | 31 | MLB | NL | ARI | 3 | 2 | .600 | 0 | 5 | 5 | 0 | 0 | 0 | 31.1 | 26 | 9 | 9 | 5 | 5 | 1 | 29 | 1 | 3 | 2.59 | 0.99 | | 2021 | 32 | MLB | NL | ARI | 7 | 11 | .389 | 0 | 27 | 27 | 0 | 0 | 0 | 158.0 | 163 | 82 | 78 | 21 | 41 | 3 | 130 | 4 | 9 | 4.44 | 1.29 | | 2022 | 33 | MLB | NL | ARI | 13 | 8 | .619 | 0 | 33 | 33 | 0 | 0 | 0 | 200.1 | 167 | 77 | 75 | 21 | 61 | 2 | 177 | 2 | 14 | 3.37 | 1.14 | | 2023 | 34 | MLB | NL | ARI | 12 | 8 | .600 | 0 | 30 | 30 | 0 | 0 | 0 | 177.2 | 143 | 71 | 65 | 20 | 68 | 0 | 187 | 4 | 19 | 3.29 | 1.19 | | 2024 | 35 | MLB | NL | ARI | 5 | 1 | .833 | 0 | 13 | 13 | 0 | 0 | 0 | 73.2 | 67 | 35 | 33 | 11 | 19 | 0 | 63 | 2 | 7 | 4.03 | 1.17 | | 2025 | 36 | MLB | NL | ARI | 9 | 6 | .600 | 0 | 22 | 22 | 0 | 0 | 0 | 128.2 | 98 | 53 | 46 | 14 | 38 | 0 | 121 | 1 | 10 | 3.22 | 1.06 | | 2025 | 36 | MLB | AL | TEX | 3 | 3 | .500 | 0 | 10 | 10 | 0 | 0 | 0 | 55.1 | 59 | 26 | 26 | 9 | 10 | 0 | 46 | 1 | 0 | 4.23 | 1.25 | | 2025 | 36 | MLB | | TOT | 12 | 9 | .571 | 0 | 32 | 32 | 0 | 0 | 0 | 184.0 | 157 | 79 | 72 | 23 | 48 | 0 | 167 | 2 | 10 | 3.52 | 1.11 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 39 | 26 | .600 | 0 | 125 | 76 | 6 | 0 | 0 | 527.0 | 467 | 225 | 199 | 28 | 194 | 2 | 379 | 26 | 0 | 3.40 | 1.25 | | Career | ARI | 62 | 50 | .554 | 0 | 162 | 162 | 0 | 0 | 0 | 953.0 | 848 | 422 | 396 | 121 | 289 | 10 | 865 | 16 | 76 | 3.74 | 1.19 | | Career | TEX | 3 | 3 | .500 | 0 | 10 | 10 | 0 | 0 | 0 | 55.1 | 59 | 26 | 26 | 9 | 10 | 0 | 46 | 1 | 0 | 4.23 | 1.25 | | Career | Majors | 65 | 53 | .551 | 0 | 172 | 172 | 0 | 0 | 0 | 1008.1 | 907 | 448 | 422 | 130 | 299 | 10 | 911 | 17 | 76 | 3.77 | 1.20 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2019 | 30 | MLB | NL | ARI | | | | | | | | | | 81.0 | 89 | 42 | 41 | 9 | 31 | 3 | 62 | 0 | 6 | 4.56 | 1.48 | | 2019 | 30 | MLB | NL | ARI | | | | | | | | | | 102.1 | 95 | 53 | 49 | 20 | 26 | 1 | 96 | 2 | 8 | 4.31 | 1.18 | | 2020 | 31 | MLB | NL | ARI | | | | | | | | | | 14.2 | 9 | 3 | 3 | 2 | 2 | 0 | 12 | 0 | 1 | 1.84 | 0.75 | | 2020 | 31 | MLB | NL | ARI | | | | | | | | | | 16.2 | 17 | 6 | 6 | 3 | 3 | 1 | 17 | 1 | 2 | 3.24 | 1.20 | | 2021 | 32 | MLB | NL | ARI | | | | | | | | | | 78.1 | 69 | 39 | 37 | 7 | 21 | 2 | 55 | 0 | 4 | 4.25 | 1.15 | | 2021 | 32 | MLB | NL | ARI | | | | | | | | | | 79.2 | 94 | 43 | 41 | 14 | 20 | 1 | 75 | 4 | 5 | 4.63 | 1.43 | | 2022 | 33 | MLB | NL | ARI | | | | | | | | | | 87.2 | 76 | 43 | 43 | 12 | 38 | 2 | 71 | 1 | 4 | 4.41 | 1.30 | | 2022 | 33 | MLB | NL | ARI | | | | | | | | | | 112.2 | 91 | 34 | 32 | 9 | 23 | 0 | 106 | 1 | 10 | 2.56 | 1.01 | | 2023 | 34 | MLB | NL | ARI | | | | | | | | | | 88.1 | 69 | 40 | 37 | 11 | 38 | 0 | 90 | 4 | 12 | 3.77 | 1.21 | | 2023 | 34 | MLB | NL | ARI | | | | | | | | | | 89.1 | 74 | 31 | 28 | 9 | 30 | 0 | 97 | 0 | 7 | 2.82 | 1.16 | | 2024 | 35 | MLB | NL | ARI | | | | | | | | | | 38.0 | 33 | 18 | 17 | 6 | 16 | 0 | 23 | 1 | 4 | 4.03 | 1.29 | | 2024 | 35 | MLB | NL | ARI | | | | | | | | | | 35.2 | 34 | 17 | 16 | 5 | 3 | 0 | 40 | 1 | 3 | 4.04 | 1.04 | | 2025 | 36 | MLB | | TOT | | | | | | | | | | 97.0 | 82 | 42 | 39 | 17 | 29 | 0 | 81 | 1 | 5 | 3.62 | 1.14 | | 2025 | 36 | MLB | | TOT | | | | | | | | | | 87.0 | 75 | 37 | 33 | 6 | 19 | 0 | 86 | 1 | 5 | 3.41 | 1.08 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 485.0 | 427 | 227 | 217 | 64 | 175 | 7 | 394 | 7 | 36 | 4.03 | 1.24 | | Career | vs RH | | | | | | | | | | 523.1 | 480 | 221 | 205 | 66 | 124 | 3 | 517 | 10 | 40 | 3.53 | 1.15 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2019 | 30 | MLB | NL | ARI | 29 | 52 | 3 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 25 | 0 | 0 | 6 | 0 | 0 | 2 | .019 | .056 | .019 | .075 | | 2021 | 32 | MLB | NL | ARI | 27 | 47 | 1 | 3 | 1 | 0 | 0 | 1 | 4 | 0 | 27 | 0 | 0 | 7 | 0 | 0 | 1 | .064 | .137 | .085 | .222 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | ARI | 56 | 99 | 4 | 4 | 1 | 0 | 0 | 3 | 6 | 0 | 52 | 0 | 0 | 13 | 0 | 0 | 3 | .040 | .095 | .051 | .146 | | Career | Majors | 56 | 99 | 4 | 4 | 1 | 0 | 0 | 3 | 6 | 0 | 52 | 0 | 0 | 13 | 0 | 0 | 3 | .040 | .095 | .051 | .146 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2019 | 30 | MLB | NL | ARI | | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .071 | .000 | .071 | | 2019 | 30 | MLB | NL | ARI | | 39 | 3 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 16 | 0 | 0 | 5 | 0 | 0 | 2 | .026 | .050 | .026 | .076 | | 2021 | 32 | MLB | NL | ARI | | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11 | 0 | 0 | 5 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2021 | 32 | MLB | NL | ARI | | 30 | 1 | 3 | 1 | 0 | 0 | 1 | 4 | 0 | 16 | 0 | 0 | 2 | 0 | 0 | 1 | .100 | .206 | .133 | .339 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | vs LH | | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 20 | 0 | 0 | 6 | 0 | 0 | 0 | .000 | .032 | .000 | .032 | | Career | vs RH | | 69 | 4 | 4 | 1 | 0 | 0 | 3 | 5 | 0 | 32 | 0 | 0 | 7 | 0 | 0 | 3 | .058 | .122 | .072 | .194 |
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