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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2012 | 18 | R | AZL | SD | 0 | 1 | .000 | 0 | 4 | 3 | 0 | 0 | 0 | 7.0 | 9 | 6 | 6 | 0 | 3 | 0 | 4 | 0 | 0 | 7.71 | 1.71 | | 2013 | 19 | A | MWL | SD | 7 | 6 | .538 | 0 | 22 | 22 | 0 | 0 | 0 | 118.2 | 110 | 53 | 36 | 7 | 31 | 2 | 86 | 4 | 0 | 2.73 | 1.19 | | 2014 | 20 | A+ | CAL | SD | 10 | 7 | .588 | 0 | 24 | 24 | 0 | 0 | 0 | 128.0 | 138 | 56 | 54 | 9 | 31 | 0 | 93 | 4 | 0 | 3.80 | 1.32 | | 2015 | 21 | AA | EAS | PHI | 8 | 6 | .571 | 0 | 23 | 23 | 0 | 0 | 0 | 131.1 | 136 | 63 | 54 | 12 | 23 | 2 | 68 | 4 | 0 | 3.70 | 1.21 | | 2016 | 22 | AAA | INT | PHI | 5 | 2 | .714 | 0 | 11 | 11 | 0 | 0 | 0 | 68.0 | 49 | 24 | 22 | 2 | 11 | 0 | 55 | 3 | 0 | 2.91 | 0.88 | | 2016 | 22 | MLB | NL | PHI | 3 | 5 | .375 | 0 | 11 | 11 | 0 | 2 | 1 | 63.1 | 67 | 42 | 39 | 12 | 17 | 1 | 31 | 1 | 5 | 5.54 | 1.33 | | 2017 | 23 | R | GCL | | 0 | 0 | --- | 0 | 2 | 2 | 0 | 0 | 0 | 7.0 | 5 | 1 | 1 | 0 | 0 | 0 | 6 | 1 | 0 | 1.29 | 0.71 | | 2017 | 23 | A+ | FSL | | 1 | 0 | 1.000 | 0 | 1 | 1 | 0 | 0 | 0 | 5.0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0.00 | 0.20 | | 2017 | 23 | AAA | INT | | 1 | 4 | .200 | 0 | 8 | 7 | 1 | 0 | 0 | 43.1 | 48 | 22 | 22 | 3 | 15 | 0 | 38 | 4 | 0 | 4.57 | 1.45 | | 2017 | 23 | MLB | NL | PHI | 1 | 5 | .167 | 0 | 11 | 11 | 0 | 0 | 0 | 64.1 | 79 | 45 | 44 | 16 | 12 | 0 | 35 | 5 | 7 | 6.16 | 1.41 | | 2018 | 24 | AAA | INT | | 2 | 2 | .500 | 0 | 4 | 4 | 0 | 0 | 0 | 20.0 | 20 | 10 | 9 | 0 | 5 | 0 | 15 | 2 | 0 | 4.05 | 1.25 | | 2018 | 24 | MLB | NL | PHI | 11 | 8 | .579 | 0 | 24 | 24 | 0 | 0 | 0 | 128.0 | 130 | 69 | 62 | 16 | 37 | 4 | 123 | 3 | 5 | 4.36 | 1.30 | | 2019 | 25 | MLB | NL | PHI | 10 | 13 | .435 | 0 | 32 | 28 | 3 | 2 | 1 | 163.1 | 172 | 88 | 75 | 28 | 48 | 5 | 129 | 6 | 15 | 4.13 | 1.35 | | 2020 | 26 | MLB | NL | PHI | 4 | 2 | .667 | 0 | 11 | 10 | 0 | 1 | 1 | 59.0 | 60 | 28 | 26 | 8 | 15 | 0 | 70 | 1 | 6 | 3.97 | 1.27 | | 2021 | 27 | MLB | NL | PHI | 4 | 7 | .364 | 0 | 18 | 18 | 0 | 0 | 0 | 105.2 | 116 | 52 | 49 | 15 | 16 | 2 | 99 | 3 | 13 | 4.17 | 1.25 | | 2022 | 28 | MLB | NL | PHI | 3 | 5 | .375 | 1 | 20 | 13 | 2 | 0 | 0 | 75.2 | 70 | 38 | 34 | 8 | 15 | 1 | 65 | 5 | 4 | 4.04 | 1.12 | | 2023 | 29 | MLB | AL | TB | 16 | 8 | .667 | 0 | 31 | 31 | 0 | 0 | 0 | 177.2 | 158 | 69 | 69 | 19 | 24 | 1 | 186 | 3 | 11 | 3.50 | 1.02 | | 2024 | 30 | MLB | AL | TB | 5 | 7 | .417 | 0 | 19 | 19 | 0 | 0 | 0 | 110.0 | 115 | 55 | 50 | 14 | 13 | 0 | 87 | 3 | 3 | 4.09 | 1.16 | | 2024 | 30 | MLB | AL | BAL | 5 | 2 | .714 | 0 | 9 | 9 | 0 | 0 | 0 | 55.1 | 51 | 16 | 16 | 8 | 11 | 0 | 47 | 0 | 3 | 2.60 | 1.12 | | 2024 | 30 | MLB | AL | TOT | 10 | 9 | .526 | 0 | 28 | 28 | 0 | 0 | 0 | 165.1 | 166 | 71 | 66 | 22 | 24 | 0 | 134 | 3 | 6 | 3.59 | 1.15 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 34 | 28 | .548 | 0 | 99 | 97 | 1 | 0 | 0 | 528.1 | 516 | 235 | 204 | 33 | 119 | 4 | 371 | 22 | 0 | 3.48 | 1.20 | | Career | PHI | 36 | 45 | .444 | 1 | 127 | 115 | 5 | 5 | 3 | 659.1 | 694 | 362 | 329 | 103 | 160 | 13 | 552 | 24 | 55 | 4.49 | 1.30 | | Career | TB | 21 | 15 | .583 | 0 | 50 | 50 | 0 | 0 | 0 | 287.2 | 273 | 124 | 119 | 33 | 37 | 1 | 273 | 6 | 14 | 3.72 | 1.08 | | Career | BAL | 5 | 2 | .714 | 0 | 9 | 9 | 0 | 0 | 0 | 55.1 | 51 | 16 | 16 | 8 | 11 | 0 | 47 | 0 | 3 | 2.60 | 1.12 | | Career | Majors | 62 | 62 | .500 | 1 | 186 | 174 | 5 | 5 | 3 | 1002.1 | 1018 | 502 | 464 | 144 | 208 | 14 | 872 | 30 | 72 | 4.17 | 1.22 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2016 | 22 | MLB | NL | PHI | | | | | | | | | | 29.1 | 35 | 20 | 19 | 9 | 9 | 1 | 9 | 0 | 2 | 5.83 | 1.50 | | 2016 | 22 | MLB | NL | PHI | | | | | | | | | | 34.0 | 32 | 22 | 20 | 3 | 8 | 0 | 22 | 1 | 3 | 5.29 | 1.18 | | 2017 | 23 | MLB | NL | PHI | | | | | | | | | | 36.2 | 45 | 32 | 32 | 11 | 9 | 0 | 21 | 2 | 4 | 7.85 | 1.47 | | 2017 | 23 | MLB | NL | PHI | | | | | | | | | | 27.2 | 34 | 13 | 12 | 5 | 3 | 0 | 14 | 3 | 3 | 3.90 | 1.34 | | 2018 | 24 | MLB | NL | PHI | | | | | | | | | | 55.2 | 64 | 37 | 34 | 9 | 21 | 3 | 57 | 1 | 0 | 5.50 | 1.53 | | 2018 | 24 | MLB | NL | PHI | | | | | | | | | | 72.1 | 66 | 32 | 28 | 7 | 16 | 1 | 66 | 2 | 5 | 3.48 | 1.13 | | 2019 | 25 | MLB | NL | PHI | | | | | | | | | | 70.2 | 75 | 41 | 35 | 17 | 34 | 3 | 56 | 1 | 7 | 4.46 | 1.54 | | 2019 | 25 | MLB | NL | PHI | | | | | | | | | | 92.2 | 97 | 47 | 40 | 11 | 14 | 2 | 73 | 5 | 8 | 3.88 | 1.20 | | 2020 | 26 | MLB | NL | PHI | | | | | | | | | | 26.0 | 29 | 18 | 17 | 7 | 10 | 0 | 35 | 1 | 2 | 5.88 | 1.50 | | 2020 | 26 | MLB | NL | PHI | | | | | | | | | | 33.0 | 31 | 10 | 9 | 1 | 5 | 0 | 35 | 0 | 4 | 2.45 | 1.09 | | 2021 | 27 | MLB | NL | PHI | | | | | | | | | | 50.0 | 53 | 24 | 22 | 7 | 8 | 0 | 49 | 1 | 3 | 3.96 | 1.22 | | 2021 | 27 | MLB | NL | PHI | | | | | | | | | | 55.2 | 63 | 28 | 27 | 8 | 8 | 2 | 50 | 2 | 10 | 4.37 | 1.28 | | 2022 | 28 | MLB | NL | PHI | | | | | | | | | | 34.0 | 38 | 21 | 21 | 4 | 9 | 0 | 29 | 3 | 1 | 5.56 | 1.38 | | 2022 | 28 | MLB | NL | PHI | | | | | | | | | | 41.2 | 32 | 17 | 13 | 4 | 6 | 1 | 36 | 2 | 3 | 2.81 | 0.91 | | 2023 | 29 | MLB | AL | TB | | | | | | | | | | 91.1 | 69 | 33 | 33 | 9 | 13 | 0 | 80 | 0 | 8 | 3.25 | 0.90 | | 2023 | 29 | MLB | AL | TB | | | | | | | | | | 86.1 | 89 | 36 | 36 | 10 | 11 | 1 | 106 | 3 | 3 | 3.75 | 1.16 | | 2024 | 30 | MLB | | TOT | | | | | | | | | | 82.1 | 71 | 33 | 31 | 11 | 16 | 0 | 74 | 1 | 3 | 3.39 | 1.06 | | 2024 | 30 | MLB | | TOT | | | | | | | | | | 83.0 | 95 | 38 | 35 | 11 | 8 | 0 | 60 | 2 | 3 | 3.80 | 1.24 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 476.0 | 479 | 259 | 244 | 84 | 129 | 7 | 410 | 10 | 30 | 4.61 | 1.28 | | Career | vs RH | | | | | | | | | | 526.1 | 539 | 243 | 220 | 60 | 79 | 7 | 462 | 20 | 42 | 3.76 | 1.17 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2015 | 21 | AA | EAS | PHI | 23 | 12 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4 | 0 | 0 | 0 | .333 | .333 | .417 | .750 | | 2016 | 22 | AAA | INT | PHI | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2016 | 22 | MLB | NL | PHI | 10 | 23 | 2 | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | .261 | .261 | .348 | .609 | | 2017 | 23 | AAA | INT | | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2017 | 23 | MLB | NL | PHI | 10 | 21 | 1 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | .143 | .143 | .143 | .286 | | 2018 | 24 | AAA | INT | | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .500 | .000 | .500 | | 2018 | 24 | MLB | NL | PHI | 24 | 44 | 3 | 4 | 0 | 0 | 1 | 1 | 0 | 0 | 31 | 0 | 0 | 6 | 0 | 0 | 0 | .091 | .091 | .159 | .250 | | 2019 | 25 | MLB | NL | PHI | 28 | 50 | 3 | 8 | 1 | 0 | 0 | 2 | 0 | 0 | 27 | 0 | 0 | 2 | 0 | 0 | 0 | .160 | .160 | .180 | .340 | | 2021 | 27 | MLB | NL | PHI | 17 | 29 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 15 | 0 | 0 | 6 | 0 | 1 | 0 | .000 | .065 | .000 | .065 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Minors | Minors | 33 | 21 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 0 | 8 | 0 | 0 | 8 | 0 | 0 | 0 | .190 | .227 | .238 | .465 | | Career | PHI | 89 | 167 | 10 | 21 | 3 | 0 | 1 | 6 | 1 | 0 | 94 | 0 | 0 | 15 | 0 | 1 | 2 | .126 | .136 | .162 | .298 | | Career | Majors | 89 | 167 | 10 | 21 | 3 | 0 | 1 | 6 | 1 | 0 | 94 | 0 | 0 | 15 | 0 | 1 | 2 | .126 | .136 | .162 | .298 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2016 | 22 | MLB | NL | PHI | | 8 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | .375 | .375 | .500 | .875 | | 2016 | 22 | MLB | NL | PHI | | 15 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | .200 | .200 | .267 | .467 | | 2017 | 23 | MLB | NL | PHI | | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2017 | 23 | MLB | NL | PHI | | 17 | 1 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | .176 | .176 | .176 | .353 | | 2018 | 24 | MLB | NL | PHI | | 8 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 2 | 0 | 0 | 0 | .125 | .125 | .125 | .250 | | 2018 | 24 | MLB | NL | PHI | | 36 | 1 | 3 | 0 | 0 | 1 | 1 | 0 | 0 | 24 | 0 | 0 | 4 | 0 | 0 | 0 | .083 | .083 | .167 | .250 | | 2019 | 25 | MLB | NL | PHI | | 22 | 2 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 10 | 0 | 0 | 2 | 0 | 0 | 0 | .227 | .227 | .227 | .455 | | 2019 | 25 | MLB | NL | PHI | | 28 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | .107 | .107 | .143 | .250 | | 2021 | 27 | MLB | NL | PHI | | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 4 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2021 | 27 | MLB | NL | PHI | | 18 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7 | 0 | 0 | 2 | 0 | 1 | 0 | .000 | .100 | .000 | .100 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | vs LH | | 53 | 5 | 9 | 1 | 0 | 0 | 1 | 0 | 0 | 31 | 0 | 0 | 8 | 0 | 0 | 2 | .170 | .170 | .189 | .358 | | Career | vs RH | | 114 | 5 | 12 | 2 | 0 | 1 | 5 | 1 | 0 | 63 | 0 | 0 | 7 | 0 | 1 | 0 | .105 | .121 | .149 | .270 |
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