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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2011 | 20 | A- | NYP | CLE | 0 | 0 | --- | 0 | 1 | 0 | 0 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0.00 | 0.50 | | 2012 | 21 | A | MWL | CLE | 0 | 0 | --- | 0 | 2 | 0 | 1 | 0 | 0 | 3.2 | 1 | 0 | 0 | 0 | 2 | 0 | 4 | 0 | 0 | 0.00 | 0.82 | | 2012 | 21 | A+ | CAR | CLE | 1 | 3 | .250 | 1 | 26 | 0 | 12 | 0 | 0 | 43.2 | 31 | 10 | 10 | 0 | 23 | 1 | 52 | 6 | 0 | 2.06 | 1.24 | | 2012 | 21 | AA | EAS | CLE | 1 | 0 | 1.000 | 3 | 17 | 0 | 7 | 0 | 0 | 20.1 | 12 | 2 | 2 | 0 | 12 | 0 | 22 | 1 | 0 | 0.89 | 1.18 | | 2013 | 22 | R | AZL | CLE | 0 | 0 | --- | 0 | 3 | 0 | 0 | 0 | 0 | 4.0 | 3 | 2 | 2 | 1 | 0 | 0 | 5 | 0 | 0 | 4.50 | 0.75 | | 2013 | 22 | AA | EAS | CLE | 2 | 3 | .400 | 0 | 30 | 0 | 5 | 0 | 0 | 33.0 | 32 | 18 | 15 | 2 | 21 | 0 | 43 | 2 | 0 | 4.09 | 1.61 | | 2014 | 23 | AA | EAS | CLE | 6 | 2 | .750 | 15 | 44 | 0 | 34 | 0 | 0 | 51.0 | 39 | 12 | 12 | 3 | 19 | 1 | 68 | 1 | 0 | 2.12 | 1.14 | | 2014 | 23 | AAA | INT | CLE | 0 | 0 | --- | 0 | 5 | 0 | 1 | 0 | 0 | 5.0 | 4 | 3 | 3 | 1 | 3 | 0 | 4 | 0 | 0 | 5.40 | 1.40 | | 2015 | 24 | AAA | INT | CLE | 1 | 2 | .333 | 16 | 46 | 0 | 27 | 0 | 0 | 49.2 | 37 | 15 | 13 | 0 | 26 | 2 | 80 | 2 | 0 | 2.36 | 1.27 | | 2015 | 24 | MLB | AL | CLE | 0 | 0 | --- | 0 | 8 | 0 | 5 | 0 | 0 | 8.0 | 5 | 2 | 2 | 1 | 2 | 0 | 11 | 0 | 1 | 2.25 | 0.88 | | 2016 | 25 | A | MWL | CLE | 0 | 0 | --- | 0 | 2 | 0 | 1 | 0 | 0 | 2.0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0.00 | 0.00 | | 2016 | 25 | AAA | INT | CLE | 3 | 1 | .750 | 9 | 47 | 0 | 22 | 0 | 0 | 49.0 | 27 | 11 | 10 | 0 | 29 | 1 | 72 | 3 | 0 | 1.84 | 1.14 | | 2016 | 25 | MLB | AL | CLE | 0 | 0 | --- | 0 | 10 | 0 | 2 | 0 | 0 | 10.2 | 9 | 3 | 3 | 1 | 5 | 2 | 7 | 0 | 1 | 2.53 | 1.31 | | 2017 | 26 | AAA | INT | | 1 | 1 | .500 | 10 | 28 | 0 | 14 | 0 | 0 | 29.1 | 27 | 10 | 10 | 3 | 11 | 0 | 36 | 2 | 0 | 3.07 | 1.30 | | 2017 | 26 | MLB | AL | CLE | 1 | 0 | 1.000 | 0 | 21 | 0 | 14 | 0 | 0 | 24.2 | 23 | 12 | 12 | 5 | 10 | 0 | 20 | 1 | 1 | 4.38 | 1.34 | | 2018 | 27 | AAA | PCL | | 2 | 5 | .286 | 15 | 49 | 0 | 30 | 0 | 0 | 56.0 | 38 | 17 | 11 | 3 | 26 | 0 | 82 | 0 | 0 | 1.77 | 1.14 | | 2018 | 27 | MLB | AL | SEA | 0 | 1 | .000 | 1 | 14 | 0 | 3 | 0 | 0 | 14.2 | 9 | 2 | 2 | 1 | 3 | 1 | 15 | 3 | 0 | 1.23 | 0.82 | | 2019 | 28 | AAA | PCL | | 0 | 0 | --- | 0 | 2 | 1 | 0 | 0 | 0 | 2.0 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0.00 | 1.00 | | 2019 | 28 | MLB | AL | SEA | 0 | 1 | .000 | 0 | 4 | 0 | 1 | 0 | 0 | 3.2 | 8 | 6 | 6 | 1 | 3 | 1 | 3 | 1 | 0 | 14.73 | 3.00 | | 2019 | 28 | MLB | AL | BAL | 1 | 0 | 1.000 | 4 | 51 | 0 | 9 | 0 | 0 | 54.1 | 58 | 32 | 31 | 7 | 26 | 0 | 60 | 3 | 4 | 5.13 | 1.55 | | 2019 | 28 | MLB | AL | TOT | 1 | 1 | .500 | 4 | 55 | 0 | 10 | 0 | 0 | 58.0 | 66 | 38 | 37 | 8 | 29 | 1 | 63 | 4 | 4 | 5.74 | 1.64 | | 2020 | 29 | MLB | AL | BAL | 2 | 0 | 1.000 | 0 | 14 | 0 | 2 | 0 | 0 | 15.0 | 9 | 6 | 3 | 1 | 3 | 0 | 14 | 1 | 3 | 1.80 | 0.80 | | 2021 | 30 | MLB | AL | BAL | 0 | 0 | --- | 0 | 20 | 0 | 8 | 0 | 0 | 20.0 | 28 | 20 | 19 | 5 | 10 | 0 | 22 | 1 | 0 | 8.55 | 1.90 | | 2021 | 30 | MLB | AL | TB | 1 | 0 | 1.000 | 0 | 11 | 0 | 3 | 0 | 0 | 16.0 | 11 | 8 | 8 | 5 | 5 | 0 | 22 | 1 | 0 | 4.50 | 1.00 | | 2021 | 30 | MLB | AL | TOT | 1 | 0 | 1.000 | 0 | 31 | 0 | 11 | 0 | 0 | 36.0 | 39 | 28 | 27 | 10 | 15 | 0 | 44 | 2 | 0 | 6.75 | 1.50 | | 2022 | 31 | MLB | NL | MIA | 0 | 0 | --- | 0 | 7 | 0 | 1 | 0 | 0 | 6.2 | 10 | 10 | 8 | 1 | 3 | 0 | 5 | 0 | 0 | 10.80 | 1.95 | | 2022 | 31 | MLB | AL | TB | 2 | 3 | .400 | 2 | 43 | 2 | 18 | 0 | 0 | 55.0 | 56 | 22 | 22 | 6 | 15 | 2 | 61 | 4 | 3 | 3.60 | 1.29 | | 2022 | 31 | MLB | | TOT | 2 | 3 | .400 | 2 | 50 | 2 | 19 | 0 | 0 | 61.2 | 66 | 32 | 30 | 7 | 18 | 2 | 66 | 4 | 3 | 4.38 | 1.36 | | 2023 | 32 | MLB | AL | TB | 1 | 0 | 1.000 | 0 | 39 | 6 | 5 | 0 | 0 | 52.0 | 36 | 12 | 8 | 2 | 11 | 0 | 54 | 4 | 2 | 1.38 | 0.90 | | 2024 | 33 | MLB | AL | TB | 2 | 2 | .500 | 1 | 38 | 7 | 4 | 0 | 0 | 46.2 | 56 | 30 | 28 | 5 | 19 | 0 | 50 | 2 | 2 | 5.40 | 1.61 | | 2024 | 33 | MLB | NL | STL | 1 | 0 | 1.000 | 0 | 11 | 0 | 3 | 0 | 0 | 12.2 | 11 | 4 | 4 | 1 | 2 | 0 | 12 | 0 | 0 | 2.84 | 1.03 | | 2024 | 33 | MLB | NL | CHN | 0 | 1 | .000 | 0 | 8 | 0 | 2 | 0 | 0 | 7.1 | 10 | 4 | 4 | 0 | 4 | 0 | 4 | 0 | 3 | 4.91 | 1.91 | | 2024 | 33 | MLB | NL | TOT | 1 | 1 | .500 | 0 | 19 | 0 | 5 | 0 | 0 | 20.0 | 21 | 8 | 8 | 1 | 6 | 0 | 16 | 0 | 3 | 3.60 | 1.35 | | 2024 | 33 | MLB | | TOT | 3 | 3 | .500 | 1 | 57 | 7 | 9 | 0 | 0 | 66.2 | 77 | 38 | 36 | 6 | 25 | 0 | 66 | 2 | 5 | 4.86 | 1.53 | | 2025 | 34 | MLB | AL | TEX | 4 | 3 | .571 | 9 | 71 | 2 | 22 | 0 | 0 | 74.0 | 40 | 21 | 19 | 5 | 20 | 0 | 74 | 6 | 4 | 2.31 | 0.81 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 17 | 17 | .500 | 69 | 302 | 1 | 154 | 0 | 0 | 350.2 | 254 | 100 | 88 | 13 | 172 | 5 | 478 | 17 | 0 | 2.26 | 1.21 | | Career | CLE | 1 | 0 | 1.000 | 0 | 39 | 0 | 21 | 0 | 0 | 43.1 | 37 | 17 | 17 | 7 | 17 | 2 | 38 | 1 | 3 | 3.53 | 1.25 | | Career | SEA | 0 | 2 | .000 | 1 | 18 | 0 | 4 | 0 | 0 | 18.1 | 17 | 8 | 8 | 2 | 6 | 2 | 18 | 4 | 0 | 3.93 | 1.25 | | Career | BAL | 3 | 0 | 1.000 | 4 | 85 | 0 | 19 | 0 | 0 | 89.1 | 95 | 58 | 53 | 13 | 39 | 0 | 96 | 5 | 7 | 5.34 | 1.50 | | Career | TB | 6 | 5 | .545 | 3 | 131 | 15 | 30 | 0 | 0 | 169.2 | 159 | 72 | 66 | 18 | 50 | 2 | 187 | 11 | 7 | 3.50 | 1.23 | | Career | FLA | 0 | 0 | --- | 0 | 7 | 0 | 1 | 0 | 0 | 6.2 | 10 | 10 | 8 | 1 | 3 | 0 | 5 | 0 | 0 | 10.80 | 1.95 | | Career | STL | 1 | 0 | 1.000 | 0 | 11 | 0 | 3 | 0 | 0 | 12.2 | 11 | 4 | 4 | 1 | 2 | 0 | 12 | 0 | 0 | 2.84 | 1.03 | | Career | CHN | 0 | 1 | .000 | 0 | 8 | 0 | 2 | 0 | 0 | 7.1 | 10 | 4 | 4 | 0 | 4 | 0 | 4 | 0 | 3 | 4.91 | 1.91 | | Career | TEX | 4 | 3 | .571 | 9 | 71 | 2 | 22 | 0 | 0 | 74.0 | 40 | 21 | 19 | 5 | 20 | 0 | 74 | 6 | 4 | 2.31 | 0.81 | | Career | Majors | 15 | 11 | .577 | 17 | 370 | 17 | 102 | 0 | 0 | 421.1 | 379 | 194 | 179 | 47 | 141 | 6 | 434 | 27 | 24 | 3.82 | 1.23 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2015 | 24 | MLB | AL | CLE | | | | | | | | | | 4.0 | 2 | 0 | 0 | 0 | 1 | 0 | 6 | 0 | 0 | 0.00 | 0.75 | | 2015 | 24 | MLB | AL | CLE | | | | | | | | | | 4.0 | 3 | 2 | 2 | 1 | 1 | 0 | 5 | 0 | 1 | 4.50 | 1.00 | | 2016 | 25 | MLB | AL | CLE | | | | | | | | | | 6.0 | 5 | 0 | 0 | 0 | 1 | 0 | 4 | 0 | 1 | 0.00 | 1.00 | | 2016 | 25 | MLB | AL | CLE | | | | | | | | | | 4.2 | 4 | 3 | 3 | 1 | 4 | 2 | 3 | 0 | 0 | 5.79 | 1.71 | | 2017 | 26 | MLB | AL | CLE | | | | | | | | | | 9.2 | 8 | 3 | 3 | 1 | 8 | 0 | 5 | 1 | 0 | 2.79 | 1.66 | | 2017 | 26 | MLB | AL | CLE | | | | | | | | | | 15.0 | 15 | 9 | 9 | 4 | 2 | 0 | 15 | 0 | 1 | 5.40 | 1.13 | | 2018 | 27 | MLB | AL | SEA | | | | | | | | | | 4.0 | 2 | 0 | 0 | 0 | 2 | 1 | 3 | 0 | 0 | 0.00 | 1.00 | | 2018 | 27 | MLB | AL | SEA | | | | | | | | | | 10.2 | 7 | 2 | 2 | 1 | 1 | 0 | 12 | 3 | 0 | 1.69 | 0.75 | | 2019 | 28 | MLB | | TOT | | | | | | | | | | 22.1 | 18 | 9 | 8 | 2 | 12 | 0 | 19 | 1 | 0 | 3.22 | 1.34 | | 2019 | 28 | MLB | | TOT | | | | | | | | | | 35.2 | 48 | 29 | 29 | 6 | 17 | 1 | 44 | 3 | 4 | 7.32 | 1.82 | | 2020 | 29 | MLB | AL | BAL | | | | | | | | | | 4.1 | 3 | 3 | 2 | 0 | 2 | 0 | 4 | 0 | 1 | 4.15 | 1.15 | | 2020 | 29 | MLB | AL | BAL | | | | | | | | | | 10.2 | 6 | 3 | 1 | 1 | 1 | 0 | 10 | 1 | 2 | 0.84 | 0.66 | | 2021 | 30 | MLB | | TOT | | | | | | | | | | 12.1 | 18 | 15 | 14 | 7 | 7 | 0 | 17 | 1 | 0 | 10.22 | 2.03 | | 2021 | 30 | MLB | | TOT | | | | | | | | | | 23.2 | 21 | 13 | 13 | 3 | 8 | 0 | 27 | 1 | 0 | 4.94 | 1.23 | | 2022 | 31 | MLB | | TOT | | | | | | | | | | 19.1 | 24 | 16 | 15 | 2 | 8 | 2 | 26 | 2 | 0 | 6.98 | 1.66 | | 2022 | 31 | MLB | | TOT | | | | | | | | | | 42.1 | 42 | 16 | 15 | 5 | 10 | 0 | 40 | 2 | 3 | 3.19 | 1.23 | | 2023 | 32 | MLB | AL | TB | | | | | | | | | | 24.2 | 19 | 5 | 3 | 1 | 5 | 0 | 24 | 1 | 1 | 1.09 | 0.97 | | 2023 | 32 | MLB | AL | TB | | | | | | | | | | 27.1 | 17 | 7 | 5 | 1 | 6 | 0 | 30 | 3 | 1 | 1.65 | 0.84 | | 2024 | 33 | MLB | | TOT | | | | | | | | | | 22.1 | 37 | 20 | 20 | 4 | 9 | 0 | 26 | 1 | 1 | 8.06 | 2.06 | | 2024 | 33 | MLB | | TOT | | | | | | | | | | 44.1 | 40 | 18 | 16 | 2 | 16 | 0 | 40 | 1 | 4 | 3.25 | 1.26 | | 2025 | 34 | MLB | AL | TEX | | | | | | | | | | 25.1 | 22 | 11 | 10 | 4 | 9 | 0 | 25 | 2 | 2 | 3.55 | 1.22 | | 2025 | 34 | MLB | AL | TEX | | | | | | | | | | 48.2 | 18 | 10 | 9 | 1 | 11 | 0 | 49 | 4 | 2 | 1.66 | 0.60 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 154.1 | 158 | 82 | 75 | 21 | 64 | 3 | 159 | 9 | 6 | 4.37 | 1.44 | | Career | vs RH | | | | | | | | | | 267.0 | 221 | 112 | 104 | 26 | 77 | 3 | 275 | 18 | 18 | 3.51 | 1.12 |
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